Turnover of ribosomal RNA in rat liver.
نویسندگان
چکیده
After a single injection of radioactive orotic acid and a "chase" of nonradioactive precursor, the specific activity of ribosomal RNA in rat liver decreases logarithmically at a rate corresponding to a half-life of about S days. The possible significance of this result is discussed with regard to control of protein synthesis.
منابع مشابه
Studies on Liver Messenger Ribonucleic Acid.
Strong evidence has accumulated in recent years in favor of the following scheme of protein biosynthesis. DNA directs the formation of complementary strands of messenger RNA which possess the necessary genetic information to determine the sequential arrangement of amino acids in polypeptide chains (1, 2). The messenger RNA attaches itself to ribosomes to form a multiple ribosomal structure, the...
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ورودعنوان ژورنال:
- Science
دوره 149 3688 شماره
صفحات -
تاریخ انتشار 1965